Summary
Overview
Work History
Education
Skills
Timeline
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Ziwei Nie

Summary

Driven by a passion for green chemistry and asymmetric catalysis, I honed my expertise at Zhao Yu, optimizing reactions for high yields and investigating reaction mechanisms. My proficiency in Matlab and Chemdraw, coupled with excellent English communication skills, facilitated significant advancements in drug molecule intermediates and colorimetric sensor development, achieving notable publication success.

Overview

8
8
years of professional experience

Work History

Research Assistant

Zhao Yu Group
08.2023 - 08.2025
  • The use of asymmetric catalysis for the tandemisation of tryptamines and hydroxyketones was investigated.
  • The asymmetric catalytic reaction was carried out by Pictet-Spengler reaction and hydrogen borrowing reaction, and high yields and high ee-values were achieved in the standard reaction conditions.
  • During the course of the study, the reaction conditions were optimised to obtain the most suitable standard conditions for the reaction, and the mechanism of the reaction was investigated in depth.

Work Study Student

Zhao Yu Group
10.2022 - 06.2023
  • Application of green chemistry to the asymmetric catalytic synthesis of intermediates of drug molecules.
  • Synthesis of a series of indole with γ-chiral ketone functionalities and recycling of chiral phosphoric acid and metal catalysts in this method.
  • Familiar with the use of NMR, GCMS, HPLC, MS.

Intern

Changchun Institute of Applied Chemistry
10.2021 - 06.2022
  • Participate in the optimization of synthetic methods for intermediates throughout the process.
  • Gained valuable experience working in the R&D industry, applying learned concepts directly to relevant work.

Graduation Project

Chen Chunxia Group
09.2019 - 05.2020
  • A series of naphthoquinone and furan derivatives were synthesized during the group period and their anticancer activities were investigated.
  • The anticancer activity of the naphthoquinone furan derivatives was investigated, and they were found to inhibit the value-added of human hepatocellular carcinoma cells, SMMC-7721, and HepG2 cell line to different degrees.

Work Study Student

Yang Guang Group
06.2017 - 06.2019
  • Design and development of colorimetric sensors for visual tracking of lead ions and VOC gases and understanding the relationship between structure and fabrication engineering of nanovesicles.
  • Preparation of histidine-fictionalized His-DA colored π-conjugated liposome for colorimetric sensors and testing of their response to different metal ions and VOC gases.
  • Publication: ‘Sensitive Colorimetric Sensor for Lead Ions and VOCs Based on Histidine-Functionalized Polydiacetylene’.

Work Study Student

09.2017 - 06.2018
  • Preparation of azobenzene substituted polydiacetylene vesicles and investigation of their discoloration behavior towards acids, bases and tetrahydrofuran after 254 nm UV illumination .
  • Publication: ‘Preparation and characterization of light-responsive azobenzene-substituted poly(diethylacetylene) vesicles’.

Education

Bachelor of Science - Chemistry

Northeast Forestry University
China
06.2020

Master of Science - Chemical of Science

National University of Singapore
Singapore
06.2023

Skills

  • Proficient in Matlab, Chemdraw, Gaussian, Word, Excel, Powerpoint, Data Analysis
  • English: Excellent listening, speaking, reading and writing skills, able to quickly navigate through literature and write reports
  • German: Currently learning German as a third language

Timeline

Research Assistant

Zhao Yu Group
08.2023 - 08.2025

Work Study Student

Zhao Yu Group
10.2022 - 06.2023

Intern

Changchun Institute of Applied Chemistry
10.2021 - 06.2022

Graduation Project

Chen Chunxia Group
09.2019 - 05.2020

Work Study Student

09.2017 - 06.2018

Work Study Student

Yang Guang Group
06.2017 - 06.2019

Bachelor of Science - Chemistry

Northeast Forestry University

Master of Science - Chemical of Science

National University of Singapore

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Ziwei Nie