Qingyuan Liang
Summary
Accomplished Senior Technical Director at BestNovo (Beijing) Medical Laboratory Co., Ltd., adept in setting up advanced molecular diagnostic platforms and leading quality management systems accreditation. Demonstrated excellence in problem-solving and team collaboration, driving significant advancements in genetic disease diagnostics and research efficiency. Proven adaptability in integrating cutting-edge technologies for enhanced scientific inquiry.
Overview
16
16
years of professional experience
1
1
Certification
Work History
Senior Technical Director
BestNovo (Beijing) Medical Laboratory Co., Ltd.
08.2013 - Current
- Setting up molecular diagnostic platforms for genetic diseases and pharmacogenomics: Long-read Sequencing (Oxford Nanopore, PacBio), Next Generation Sequencing (illumina, MGI), Sanger Sequencing and its derivatives (Thermo Fisher Scientific), MLPA, aCGH/SNP array, Optical Genome Mapping (Bionano Genomics), MassARRAY System (Agena Bioscience), real-time PCR, etc.
- Establishment of a quality management system, accredited by Medical Laboratory Accreditation-ISO 15189.
- Responsible for College of American Pathologists (CAP) Proficiency Testing (PT) programs and National Center for Clinical Laboratories (NCCL) External Quality Assessment (EQA) programs.
- Finding genes associated with a disease, designing custom targeted NGS panels, and developing kits for diagnosing specific genetic diseases.
- Genome variant classification and interpretation according to ACMG Standards and Guidelines.
- Utilizing cutting-edge technologies (Transcriptomics, Epigenomics, Single Cell & Spatial Omics and Olink) to help co-researchers' scientific research.
- Mentored junior team members, fostering professional growth and skill development.
- Implemented innovative technologies to enhance product performance and user experience.
- Managed vendor relationships to secure timely delivery of products and services at competitive pricing.
- Improved project efficiency by streamlining workflows and implementing agile methodologies.
- Spearheaded efforts in research and development, identifying cutting-edge technologies that drove significant advancements within the company.
Research Assistant
NUS Dr. Ana Sauri's Laboratory
09.2011 - 06.2013
- Participated actively in regular meetings with fellow researchers to discuss project updates, challenges faced, and lessons learned during ongoing activities.
- Organized research materials, maintaining a well-ordered workspace conducive to productivity.
- Conducted literature reviews to support hypothesis development and identify gaps in existing knowledge.
- Implemented rigorous quality control measures, elevating standard of research outputs.
- Optimized lab equipment usage, significantly reducing operational costs and downtime.
- Developed new protocols and improved existing laboratory processes.
Research Assistant
Department of Molecular Microbiology, VU Amsterdam
09.2009 - 06.2011
- Collaborated with researchers and scientists to design and execute experiments.
- Managed laboratory equipment and resources, ensuring proper maintenance and optimal functionality.
- Analyzed results using analytical software and created reports.
- Cooperated with other technicians to develop and test new protocols.
- Interpreted laboratory results to provide technical advice to scientists.
Education
Master of Science - Molecular Biology
Vrije Universiteit Amsterdam
Amsterdam, Netherlands07.2009
MBA - Business Administration And Management
Hogeschool Van Amsterdam
Amsterdam, Netherlands09.2007
Bachelor of Science - Biotechnology
Hubei University
Wuhan, China07.2004
Skills
- Problem-Solving
- Multitasking Abilities
- Organizational Skills
- Adaptability and Flexibility
- Decision-Making
- Task Prioritization
- Analytical Thinking
- Risk Management
- Team Collaboration
Accomplishments
Achieved 30 patents by collaborating with team
- Mutant gene related to pulmonary hypertension and application thereof (CN114032302B)
- Reagent for detecting novel pathogenic gene TTN of dilated cardiomyopathy and application thereof (CN115961019B)
- Reagent for detecting MYBPC3 mutant gene and application thereof (CN115948533B)
- Arrhythmia right ventricular dysplasia cardiomyopathy variant gene CDH2 and application thereof (CN115786356B)
- Familial thoracic aortic aneurysm mutant gene and application thereof (CN113913437B)
- Mutant gene related to hereditary arrhythmia and application thereof (CN114015697B)
- Mutated genetic arrhythmia gene and application thereof (CN113957075B)
- Multiple-target capture kit for familial hypercholesterolemia and detection method thereof (CN113684270B)
- Familial hypercholesterolemia gene detection library construction method and kit thereof (CN113684269B)
- Mutant FBN1 gene and Marfan Syndrome detection kit (CN114214398B)
- Mutated TTN gene and hypertrophic cardiomyopathy detection kit (CN114317708B)
- Mutant dilated cardiomyopathy pathogenic gene TTN and application thereof (CN113981066B)
- Gene mutation fragment related to special diabetes and application thereof (CN113817813B)
- Mutant gene related to hereditary glomerular disease and application thereof (CN114085900B)
- Congenital heart disease mutant gene and application thereof (CN114032300B)
- Familial hypercholesterolemia related gene, detection kit and application thereof (CN113667665B)
- Mutant hypertrophic cardiomyopathy pathogenic gene MYBPC3 and application thereof (CN114107312B)
- Mutant gene related to rare genetic disease and application thereof (CN113957138B)
- Mutant gene capable of causing myocardial hypertrophy and application thereof (CN113881767B)
- Mutant Marfan Syndrome pathogenic gene FBN1 and application thereof (CN113980971B)
- Early-onset coronary heart disease related gene and detection reagent and application thereof (CN113136387B)
- HCN4 mutant gene, mutant and Brugada Syndrome detection kit (CN113584156B)
- SCN5A mutant gene, application and Brugada Syndrome detection kit (CN113637739B)
- LAMP2 mutant gene, mutant and Danon disease detection kit (CN113637674B)
- Novel mutant protein related to long QT syndrome, novel mutant gene and application thereof (CN111423503B)
- Novel mutant protein related to dilated cardiomyopathy, novel mutant gene and application thereof (CN112028983B)
- Early-onset coronary heart disease gene detection kit (CN112322718B)
- A specimen sampling device for medical testing (CN221685978U)
- A kind of kit (CN207566060U)
- A kind of kit (CN207001287U)
Certification
ISO15189 Internal Auditor
Languages
English
Advanced (C1)
Chinese (Mandarin)
Bilingual or Proficient (C2)
Timeline
Senior Technical Director
BestNovo (Beijing) Medical Laboratory Co., Ltd.
08.2013 - Current
Research Assistant
NUS Dr. Ana Sauri's Laboratory
09.2011 - 06.2013
Research Assistant
Department of Molecular Microbiology, VU Amsterdam
09.2009 - 06.2011
Master of Science - Molecular Biology
Vrije Universiteit Amsterdam
MBA - Business Administration And Management
Hogeschool Van Amsterdam
Bachelor of Science - Biotechnology
Hubei University
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