Summary
Overview
Work History
Education
Skills
Websites
Research Interests
References
Interests
Timeline
Generic

NECLA GUVEN

Strong Academic And Industrial Background Seeking PhD (Starting September 2026)
Paris - Lyon

Summary

Final-year biotechnology engineering student at SupBiotech Paris and recipient of the Sanofi NextGen Scholarship. Possessing over 4 years of experience in molecular biology, gene delivery, and mRNA technologies from work at Sanofi's mRNA Center of Excellence and current research internship at the National University of Singapore. Passionate about translational research and gene therapy, actively pursuing a PhD opportunity starting in September 2026 within Roche's innovative environment in Basel.

Overview

8
8
years of professional experience
2026
2026
years of post-secondary education
3
3
Languages

Work History

Research Intern

National University of Singapore
06.2025 - 09.2025
  • Performed cell culture and LNP synthesis for gene and protein delivery
  • Assessed transfection outcomes using Western blot and FACS
  • Contributed to non-viral delivery research in a biomedical context

Molecular and cellular biology Engineer at mRNA CoE

Sanofi Vaccines
09.2023 - Current

Apprenticeship, work-study contract - Sanofi NextGen Scholar

  • Conducted cell culture and in vitro assays following mRNA transfection
  • Analyzed RNA expression via Western blot and flow cytometry (FACS)
  • Performed mRNA characterization using HPLC and mass spectrometry
  • Recorded and managed experimental data in the electronic lab notebook.
  • Led bibliographic research and initiated innovative projects on in vitro mRNA translation mechanisms

Technician in Research Support

Sanofi Vaccines
09.2022 - 08.2023

Apprenticeship, work-study contract

  • Performed macrophage cell culture and LNP transfection assays
  • Designed and executed toxicity and functionality tests
  • Contributed to automated screening processes and supported early development workflows
  • Apprenticeship, work-study contract

Multipurpose Employee

Mcdonald's
01.2021 - 12.2022

Student contract

  • Managed shift teams and ensured operational efficiency
  • Prepared food orders and maintained hygiene standards in fast-paced environments

Research laboratory technician

Mines Saint-Étienne Graduate School of Engineering
01.2020 - 12.2020

4-month internship & fixed-term contract during holidays

  • Maintained cell cultures and monitored experimental timelines
  • Conducted toxicity assays (LDH, TNF-alpha, ROS, ELISA)
  • Designed experimental plans and documented procedures in laboratory notebooks

Hospital duty officer

Argentière Retirement Home
01.2018 - 12.2020
  • Maintained cleanliness and hygiene of rooms and shared spaces
  • Supported elderly residents in daily routines with respect and discretion
  • Collaborated with healthcare staff

Education

Engineering School (Apprenticeship) - Biotechnology

SupBiotech
Paris
09-2026

Bachelor of Science - Biotechnology

University Claude Bernard Lyon
Lyon
9 2022 - 8 2023

Two-year Higher National Diploma (BTS) - Biotechnology

High School Honoré D'Urfé
Saint-Etienne
09.2020 - 8 2022

French Scientific Baccalaureate - Maths, Physics, Biology

High School Ella Fitzgerald
Vienne
09.2017 - 8 2020

Skills

Cell and Molecular Biology

  • Cell culture (under PSM / BSL-2), RNA/DNA transfection

  • DNA/RNA extraction, PCR, RT-PCR, ddPCR

  • SDS-PAGE, Western blot, ELISA

  • Genotoxicity and toxicity assays

  • Test of macrophage-cell killing

  • LNP-cell binding assays

  • Implementation of experimental plans

  • Writing of laboratory notebooks

Analytical Techniques

  • Chromatography: HPLC, CPG

  • Flow cytometry (FACS IQUE3), Vi-Cell Blue

  • Use of fluorescence inverted microscope

  • Laboratory Equipment & Automation

  • Echo550, ViaFlo, Zéphyr, Multidrop

Teamwork Critical thinking Rigour Priority setting Curiosity Versatility

Research Interests

  • Design and characterization of organ-targeted lipid nanoparticles for mRNA-based therapeutics
  • Engineering lipid nanoparticles for efficient cytosolic delivery of CRISPR-Cas components in primary cells
  • Optimizing mRNA stability and translation efficiency through novel nucleotide modifications and UTR engineering
  • Investigating intracellular trafficking mechanisms of mRNA-loaded nanoparticles for enhanced endosomal escape

References

Pr Jérémie Pourchez - Research director | Mines Saint-Étienne Graduate School of Engineering.

Dr Isabelle Legastelois - Head of RNA Sciences | Sanofi Vaccines.

Dr Andy Tay Kah Ping - Presidential Young Professor and Principal Investigator at National University of Singapore

Interests

Travel
Photography
Member of humanitarian associations

Timeline

Research Intern

National University of Singapore
06.2025 - 09.2025

Molecular and cellular biology Engineer at mRNA CoE

Sanofi Vaccines
09.2023 - Current

Technician in Research Support

Sanofi Vaccines
09.2022 - 08.2023

Multipurpose Employee

Mcdonald's
01.2021 - 12.2022

Two-year Higher National Diploma (BTS) - Biotechnology

High School Honoré D'Urfé
09.2020 - 8 2022

Research laboratory technician

Mines Saint-Étienne Graduate School of Engineering
01.2020 - 12.2020

Hospital duty officer

Argentière Retirement Home
01.2018 - 12.2020

French Scientific Baccalaureate - Maths, Physics, Biology

High School Ella Fitzgerald
09.2017 - 8 2020

Engineering School (Apprenticeship) - Biotechnology

SupBiotech

Bachelor of Science - Biotechnology

University Claude Bernard Lyon
9 2022 - 8 2023
NECLA GUVENStrong Academic And Industrial Background Seeking PhD (Starting September 2026)