Summary
Work History
Education
Skills
Publications
AWARDS AND SCHOLARSHIPS
Timeline
Generic

Liang Yajing

Research Fellow

Summary

Accomplished and skilled Postdoctoral Research Fellow with extensive experience in collaborative laboratory settings. My training provides me with the ability to effectively communicate complex scientific concepts to diverse audiences, including those outside my field. I am eager to explore new opportunities that will allow me to broaden my horizons, leverage my expertise, and further nurture my passion for research and scientific communication.

Work History

Research Fellow

National University of Singapore
10.2024 - Current
  • Conceptualised and conducted pilot experiments for paper publication.
  • Drafted, revised, and collated data for grant application.
  • Drafted and revised the IACUC mouse protocol.
  • Established partnerships and collaboration with other labs.
  • Mentored undergraduate and postgraduate students.

Education

Ph.D. - Yong Loo Lin School of Medicine

National University of Singapore
Singapore
04.2001 -

Master of Science - Cell Biology

Zhejiang University
China
04.2001 -

Bachelor of Science - Bio-science

Shenzhen University
China
04.2001 -

Skills

  • Protein expression
  • Antibody preparing
  • Protein purification
  • Mouse breeding
  • Mouse intraperitoneal injection
  • Mouse tissue isolation
  • Mouse embryo NSC isolation
  • Cell culture
  • NSC differentiation
  • Lentiviral transduction
  • Overexpression constructions cloning
  • shRNA constructions cloning
  • CRISPR/Cas-9 genome editing
  • RNA extraction
  • qRT-PCR
  • Immunoblotting
  • Immunofluorescence
  • Chromatin immunoprecipitation
  • Immunoprecipitation
  • Telomere Dysfunction Induced Foci (TIF) analysis

Publications

  • Y. Liang., O. V. Grinchuk, N. O. Cipta, Y. Zeng, Y. H. Chuah, J. Yoon, Z. J. Khong, H. Y. Chow, S. Y. Ng, Y. H. Loh and D. S. T. Ong (2025). “DMTF1 transcriptionally activates chromatin organization genes to promote E2F1-conducive chromatin conformation for neural stem cell proliferation.” Nucleic Acids Res. Under revision.


  • Feng, J., Y. H. Chuah, Y. Liang, N. O. Cipta, Y. Zeng, T. Warrier, G. Elfar, J. Yoon, O. V. Grinchuk, E. X. Y. Tay, K. Z. Lok, Z. Q. Zheng, Z. J. Khong, Z. S. Chong, J. Teo, E. M. Sanford, C. J. Y. Neo, H. Y. Chiu, J. Y. Leung, L. C. Wang, Y. T. Lim, T. Zhao, R. M. Sobota, K. C. Crasta, V. Tergaonkar, R. Taneja, S. Y. Ng, C. F. Cheok, S. C. Ling, Y. H. Loh and D. S. T. Ong (2024). "PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin." Nucleic Acids Res 52(12): 7063-7080.


  • Lee, B. W. L., Y. H. Chuah, J. Yoon, O. V. Grinchuk, Y. Liang, J. L. Hirpara, Y. Shen, L. C. Wang, Y. T. Lim, T. Zhao, R. M. Sobota, T. T. Yeo, A. L. A. Wong, K. Teo, V. D. W. Nga, B. W. Q. Tan, T. Suda, T. B. Toh, S. Pervaiz, Z. Lin and D. S. T. Ong (2024). "METTL8 links mt-tRNA m(3)C modification to the HIF1alpha/RTK/Akt axis to sustain GBM stemness and tumorigenicity." Cell Death Dis 15(5): 338.


  • Harley, J., M. M. Santosa, C. Y. Ng, O. V. Grinchuk, J. H. Hor, Y. Liang, V. J. Lim, W. W. Tee, D. S. T. Ong and S. Y. Ng (2024). "Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes." Biogerontology 25(2): 341-360.


  • Chuah, Y. H., E. X. Y. Tay, O. V. Grinchuk, J. Yoon, J. Feng, S. Kannan, M. Robert, R. Jakhar, Y. Liang, B. W. L. Lee, L. C. Wang, Y. T. Lim, T. Zhao, R. M. Sobota, G. Lu, B. C. Low, K. C. Crasta, C. S. Verma, Z. Lin and D. S. T. Ong (2023). "CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma." Cell Death Differ 30(8): 1973-1987.


  • Wang, L. M., K. Jia, Z. F. Li, H. Y. Qi, D. X. Liu, Y. J. Liang, S. L. Hao, F. Q. Tan and W. X. Yang (2023). "TiO(2) nanoparticles affect spermatogenesis and adhesion junctions via the ROS-mediated mTOR signalling pathway in Eriocheir sinensis testes." Environ Pollut 331(Pt 2): 121952.


  • Liang, Y. J., J. H. Ni, L. M. Wang, F. Q. Tan and W. X. Yang (2020). "KIF3A regulates the Wnt/beta-catenin pathway via transporting beta-catenin during spermatogenesis in Eriocheir sinensis." Cell Tissue Res 381(3): 527-541.


  • Liang, Y. J. and W. X. Yang (2019). "Kinesins in MAPK cascade: How kinesin motors are involved in the MAPK pathway?" Gene 684: 1-9.


AWARDS AND SCHOLARSHIPS

  • NUS Research Scholarship (2020-2024)
  • Chinese National Scholarship (2019)
  • Shenzhen University Outstanding Graduate (2017)
  • Shenzhen University First-class scholarship (2013-2016)
  • Chinese National Inspirational Scholarship (2013-2016)

Timeline

Research Fellow

National University of Singapore
10.2024 - Current

Ph.D. - Yong Loo Lin School of Medicine

National University of Singapore
04.2001 -

Master of Science - Cell Biology

Zhejiang University
04.2001 -

Bachelor of Science - Bio-science

Shenzhen University
04.2001 -
Liang Yajing Research Fellow