Summary
Overview
Work History
Education
Skills
Languages
Timeline
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Kim-Tien, Ng

Kim-Tien, Ng

Summary

Dynamic and results-driven professional with a Ph.D. in Molecular Virology and Evolutionary Biology, recognized for pioneering advancements in viral detection and quantification. I developed and patented a novel assay for rhinovirus quantification, significantly improving disease prognosis assessments and antiviral treatment monitoring. My research delineated the evolutionary history of EV-D68, providing critical insights during unprecedented outbreaks in the U.S.

I have received multiple prestigious awards, including recognition at the 64th Meeting of Nobel Laureates in Physiology and Medicine for Young Scientist (Lindau, Germany) and the 21st CROI Young Investigator Award (Boston, USA). As a Research Associate at Duke-NUS Medical School, I designed innovative peptide libraries for disease outbreak response, and at the National University of Singapore, I optimized SARS-CoV-2 isolation protocols and enhanced detection tools.

With nearly three years of experience as a Scientific Officer in a diagnostic cancer company, I successfully scaled robotic process automation to improve operational efficiency and contributed to achieving College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) accreditations. Currently, as a Program Manager at Xenolis Pte Ltd, I lead cutting-edge projects that utilize six-letter ExSELEX technology to develop XenoAptamer-based innovative diagnostic tools and therapeutics, driving our mission to address global health challenges through strategic planning and collaborative research initiatives.

Overview

7
7
years of professional experience

Work History

Programme Manager

Xenolis Pte. Ltd.
06.2024 - Current
  • Led cutting-edge projects that utilize six-letter ExSELEX technology to develop XenoAptamer-based innovative diagnostic tools and therapeutics, driving our mission to address global health challenges through strategic planning and collaborative research initiatives.
  • Managed administrative and daily projects progress, complying with policies and regulations.
  • Established strong relationships with key stakeholders and collaborators, ensuring support for project initiatives.
  • Developed strategic plans, setting clear objectives and achievable milestones for the team.
  • Managed cross-functional teams for successful project completion within deadlines and budgets.

Research Scientist

Xenolis Pte. Ltd.
02.2024 - 06.2024
  • Utilized expertise in medical virology and evolutionary biology to help with design and development of XenoAptamer.
  • Streamlined research processes to meet tight deadlines for multiple projects.
  • Maintained a safe working environment by enforcing strict adherence to laboratory safety guidelines.
  • Evaluated new technologies for potential integration into existing research processes, driving continuous improvement efforts.

Production Scientist

Axil Scientific Pte. Ltd.
01.2023 - 01.2024
  • Contributed to continuous improvement efforts by suggesting and implementing process enhancements.
  • Maintained a safe work environment, adhering to all safety protocols and guidelines.
  • Performed thorough data analysis to identify trends and areas for potential improvement in the production process.
  • Assisted in troubleshooting technical issues during production runs, minimizing downtime and delays in project timelines.
  • Collaborated with cross-functional teams to troubleshoot issues and improve overall productivity.
  • Conducted research on emerging industry trends or technologies, incorporating findings into current processes as appropriate.
  • Maintained detailed records of all experiments performed, results obtained, and conclusions drawn, ensuring accurate documentation and easy reference for future projects.

Senior Research Fellow

Agency for Science, Technology and Research
05.2022 - 12.2022
  • Improved and maintained cell lines (Hep38.7, HepG2-NTCP, HepG2, H1299, Cos-7, 293FT) for hepatitis B virus (HBV) and coronavirus experiments.
  • Planned and executed experiments involving HBV and primary human hepatocytes in BSL2 facilities.
  • Improved and validated the nucleic acid extraction and the qPCR protocol for HBV quantification.
  • Planned and trained personnel the production of SARS-CoV-2 and Influenza A pseudoviruses using the Non-advanced Lentivirus system in BSL-2+ facility.
  • Tested, optimized, and validated ELISA and immunofluorescence assay for human coronaviruses.

Senior Scientist

ThermoFisher Scientific
01.2022 - 05.2022
  • Managed multiple concurrent projects with strict deadlines, prioritizing tasks effectively to maintain progress without sacrificing quality or accuracy.
  • Contributed to risk assessment efforts, identifying potential hazards and implementing appropriate mitigation strategies to safeguard personnel and resources.
  • Involved in training and guiding of junior scientists, reviewed, and approved other scientist’s work.
  • Verified and validated new qPCR diagnostics workflow for respiratory viruses.

Research Fellow

National University of Singapore, NUS
07.2020 - 01.2022
  • Enhanced research quality by implementing rigorous methodologies and data analysis techniques.
  • Mentored junior researchers, providing guidance on study design, data analysis, and manuscript preparation.
  • Ensured the highest standards of scientific integrity were upheld throughout all stages of the research process.
  • Maintained accurate records of experimental procedures, observations, and findings for transparent reporting of results in publications.
  • Planned and executed experiments (isolation, amplification, quantification, and neutralization) involving live SARS-CoV-2 in BSL-3 facilities.
  • Involved in the establishment of BSL-3 Standard Operating Procedure (SOP) for SARS-CoV-2
  • Planned and executed experiments involving SARS-CoV-2 and Influenza A pseudoviruses in BSL-2+ facility.
  • Maintained cell lines (H1299, Cos-7, 293FT, CHO, CHO-ACE2, MRC5, MDCK, Huh7.5, VeroE6) human coronaviruses and Influenza A experiments
  • Active involvement in audits and inspections conducted by Ministry of Health (MOH) Singapore and NUS Office of Safety, Health and Environment (OSHE).

Scientific Officer

Lucence Diagnostics Pte
01.2018 - 06.2020
  • Headed the automation project: automated and transited 70% of bench-top or manual laboratory processes (nucleic acid extraction, qPCR setup and NGS library preparation and clean-up) into fully automated procedures.
  • Designed, developed, and executed integration testing. Managed to improve operational efficiency, productivity, and quality, while reducing manhours by at least 50%.
  • Reviewed, wrote, executed, and documented test plans and reports that meet international standard (ISO13485 and CAP).
  • Played a key role in achieving company’s accreditations which include (a) ISO 15189, (b) College of American Pathologist (CAP) and (c) Clinical Laboratory Improvement Amendments (CLIA).
  • Involved in the development, validation, and automation of NGS assays to bring the technology efficiently from bench to bedside.
  • Involved in the establishment and setup of SARS-CoV-2 lab to support national needs for COVID-19 testing.

Education

Ph.D. - Medical Virology And Evolutionary Biology

University of Malaya
Malaysia
06-2020

Skills

  • Team leadership and direction
  • Policy and procedure improvements
  • Team training and development
  • Performance monitoring
  • Documentation proficiency
  • Professional writing

Languages

English
Bilingual or Proficient (C2)
Malay
Bilingual or Proficient (C2)
Chinese (Mandarin)
Upper intermediate (B2)

Timeline

Programme Manager

Xenolis Pte. Ltd.
06.2024 - Current

Research Scientist

Xenolis Pte. Ltd.
02.2024 - 06.2024

Production Scientist

Axil Scientific Pte. Ltd.
01.2023 - 01.2024

Senior Research Fellow

Agency for Science, Technology and Research
05.2022 - 12.2022

Senior Scientist

ThermoFisher Scientific
01.2022 - 05.2022

Research Fellow

National University of Singapore, NUS
07.2020 - 01.2022

Scientific Officer

Lucence Diagnostics Pte
01.2018 - 06.2020

Ph.D. - Medical Virology And Evolutionary Biology

University of Malaya
Kim-Tien, Ng