Gayathri Rajamanickam

Ambitious, productive, and innovative pharmaceutical chemist with a PhD and experience in drug discovery, formulation development, and pharmacological evaluation for various neurological disorders. Having more than 12 years of pharmaceutical sciences research and teaching expertise. Extensively published in scientific journals with the knowledge of pharmaceutical sciences. Expertise in defining adult-learning strategies. A confident presenter at conferences and lecturer in classrooms, able to explain complex information to audiences of all levels. Proven ability to lead cross-functional teams and deliver high-quality results on time and within budget. Seeking an opportunity to impact patient lives through pharmaceutical innovation. Detail-oriented, highly motivated, and able to prioritize work to meet deadlines. Strong verbal, written, and interpersonal communication skills with excellent judgment and problem-solving skills. Proven ability to lead cross-functional teams and deliver high-quality results on time.

• St. Peter institute of Pharmaceutical Sciences Gold medal for securing the highest marks in the M.Pharm in JSS University.
• Qualified in All India Council for Technical Education (AICTE) Sponsorship cum stipend for M.Pharm course.

• Life Member and Registered Pharmacist (10484-A1), Pharmacy Council of India
• Trainee in the Department of Anatomy, All India Institute of Medical Sciences (AIIMS), New Delhi, India
• Head of examination Unit, Faculty of Pharmacy, Quest International University, Malaysia
• Occupational Safety and Health Administration (OSHA) member- Faculty of Pharmacy, Quest International University, Ipoh, Perak, Malaysia.
• Responsible care and use of laboratory animal course (RCULAC) conducted by Sing Health experimental medicine centre and sing health office of research.

• Chitosan nanoparticles encapsulated with natural flavonoid niruriflavone mitigate neurobehavioral deficits, biochemical alteration, and histopathological changes in aluminium chloride-induced Alzheimer’s disease rats, Neurodegenerative Diseases: Biology & Therapeutics conference, Cold Spring Harbor Laboratory, New York, United States of America, November 30 - December 3, 2022
• Amelioration of lipid peroxidation in-vivo by niruriflavone-loaded chitosan nanoparticle in aluminium chloride-induced Alzheimer's disease rats, International Conference on Advanced Nanomaterials and Applications (ICANA 2022), School of Advanced Sciences, VIT-AP University, India and Indiana University-Purdue, University Indianapolis (IUPUI), USA, 16th-18th November 2022
• Effect of Niruriflavone on Neuronal Viability in Aluminium Chloride-Induced Alzheimer’s Disease Rats, Monash Initiate Sep 2022, Monash University, Malaysia
• In-vitro neuroprotective potential of ethyl acetate fraction from hydroalcoholic extract of Phyllanthus niruri, 3rd International Conference of Pharmacy and Health Sciences 2021 (ICPHS 2021), University of Kuala Lumpur Royal College of Medicine Perak (UniKL RCMP), Malaysia, 2-3 rd August 2021
• A Facile Synthesis of Quinoxaline-2, 3-dione derivatives as Neuroprotective agent in ethidium bromide induced neurodegenerative rat models, 2nd International conference on recent advances in health sciences, Lincoln university college, Malaysia, 14-16th August 2014
• Effect of Tamoxifen on Cardiac Morphology in Ovariectomized Rat, 2nd International conference on recent advances in health sciences, Lincoln university college, Malaysia, 14-16th August 2014

• Neuroprotective effects of chitosan nanoparticles loaded with niruriflavone in an aluminium chloride-induced Alzheimer's disease rat model, Toxicol.environ. Health sci., 2024, Accepted for Publication
• Formulation and characterization of chitosan nanoparticles loaded with neuroprotective flavonoid from Phyllanthus niruri Linn., Macromol. Res., 2023, 31, 1, 13-24
• Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of Aluminium chloride-induced neurobehavioral and biochemical changes in an animal model, Med Chem Res., 2022, 31, 1740–53
• A review on phyto-nanotechnology for therapy of Alzheimer’s disease, Indian Journal of Biochemistry & Biophysics, 2022, 59, 867-872
• Synthesis, spectral characterization, anti-bacterial, cytotoxic evaluation and docking studies of new urea and thiourea derivatives, Indian Journal of Biochemistry and Biophysics, 2022, 59, 767-776
• Identification and Comparative Study of Invitro Antioxidant Potential of Fractionated Hydroalcoholic Extract of Phyllanthus niruri Linn., European Journal of Advanced Chemistry Research, 2020, 1, 1, 1-8
• Prevention of Cardiac Myocyte Changes by Raloxifene, a Selective Estrogen Receptor Modulator (SERM) in Rat Model of Surgically Induced Estrogen Depleted State, International Journal of Medical Research & Health Sciences, 2017, 6, 9, 139-50
• A facile synthesis and neuroprotective role of novel quinoxaline2,3-bis hydrazones in ethidium bromide-induced demyelinated rats, Medicinal Chemistry Research, 2016, 10.1007/s00044-016-1572-4
• Synthesis, characterization, and pharmacological evaluation of some potent 2-(substituted phenylimino) quinoxaline-3-one for their analgesic activity, Journal of Chemical and Pharmaceutical Research, 2015, 7, 7, 961-966
• In vitro anthelmintic and antimicrobial activity of novel series of quinoxaline-2, 3-dione -6-sulphonyl Benzimidazole (s), Journal of Chemical and Pharmaceutical Sciences, 2015, 8, 4, 656-660
• Synthesis and cardioprotective effect of novel series of combination of Quinazoline – Thiadiazole against Isoproterenol induced Hypertrophy, Malaysian Journal of Pharmacy, 2015, 2, 1, 152
• Augmentation of Humoral immunity by an Ayurvedic Herbal preparation, Anantamul salsa Invitro, Malaysian Journal of Pharmacy, 2015, 2, 1, 177
• Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives, The Scientific World Journal, 2012, 2012, 718023, 1-8
• Synthesis and Characterization of some Novel Quinoxaline-2, 3-Dione Derivatives: A Preliminary Investigation on their Activity against a Human Epithelial Carcinoma Cell Line, Letters in Drug Design & Discovery, 2011, 8, 317-320
• Design, synthesis, and docking studies of novel ofloxacin analogues as antimicrobial agents, Medicinal Chemistry Research, 2011, 10.1007/s 00044 011-9655-8
• New Benzimidazolo Indane-1, 3-Dione Derivatives: Synthesis and In-vitro Screening Against Helminthic Infections, International Journal of Drug Design and Discovery, 2011, 1, 2, 506-509
• Pharmacological Evaluation of Clerodendrum Philippinum Schauer Flowers for Antianxiety and Central Nervous System Depressant Activity, International Journal of Pharmaceutical Research, 2010, 2, 2, 13-15

• Prof. Datuk Dr. Allan Mathews. Ph.D, Dean and Professor, Faculty of Pharmacy, Quest International University Perak, Ipoh, Malaysia, +60198810483, allan.mathews@qiup.edu.my
• Assoc. Prof. Dr. Venkatesh Sundararajan. Ph.D, Associate Professor, Department of Physiology, Pharmacology & Toxicology, West Virginia University School of Medicine, Morgantown, United States, 304-293-9785, +1 (551) 689-3280
• Prof. Dr. S.L. Manju, Ph.D, Professor, Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Vellore, India, +91-9003777645, slmanju@vit.ac.in
• Assoc.Prof.Dr. S. Jubie, M. Pharm, Ph.D, Associate Professor, Department of Pharmaceutical Chemistry, J. S. S. College of Pharmacy, Rockland, Ooty, 643 001, Tamil Nadu, India, +91-9894618588, jubiejawahar@gmail.com